Hemp agrimony is an old European herb used for digestion, liver complaints, and mild respiratory problems. If you’ve seen it in wild hedges or herbal books, you might wonder whether it’s worth trying. This page explains the traditional uses, what modern evidence actually says, and the safety steps you must take before using it.
Traditionally, people used hemp agrimony as a bitter tonic for the liver and digestion, as a mild diuretic, and sometimes for coughs or low-grade fevers. Herbalists also applied it externally for minor wounds and swollen skin. Those uses come from centuries of folk medicine, not large modern trials.
Modern scientific studies on hemp agrimony are limited. A handful of lab and animal studies suggest the plant has anti-inflammatory and antioxidant compounds, but that doesn’t translate directly into safe, proven benefits in people. Think of hemp agrimony as a historic herbal tool with hints of activity, not a clinically proven medicine.
Here’s the key: many Eupatorium species can contain pyrrolizidine alkaloids (PAs), chemicals that can damage the liver with long or heavy use. That risk changes the whole conversation. Because of PAs, most experts recommend avoiding long-term internal use of hemp agrimony, and pregnant or breastfeeding people should not take it at all.
If you still want to try it, do these three things: 1) Talk with your healthcare provider first, especially if you take other meds or have liver disease. 2) Use only short, occasional courses rather than daily long-term use. 3) Buy from a reputable seller that tests for contaminants and lists the botanical name (Eupatorium cannabinum) and batch testing info.
Forms you might see: dried herb for short teas, liquid tinctures, or topical preparations. Topical use reduces systemic exposure, but check the label and avoid broken skin if you have sensitive skin or allergies. If you’re looking for liver support and want a better-studied option, ask about milk thistle (silymarin) — it has a clearer safety profile and more clinical data.
Practical tips: never mix hemp agrimony with alcohol or other liver-stressing substances, stop use if you feel unwell or notice stomach pain, fatigue, jaundice or dark urine, and keep doses conservative. If you’re sourcing the herb, avoid wild-harvested plants unless you’re certain of the identification; many look-alike plants can appear in hedgerows.
Hemp agrimony has history and some promising lab signals, but safety concerns mean it’s not a casual pick. Ask questions, get quality products, and prefer short-term, cautious use rather than ongoing self-treatment.