If a doctor prescribed a cephalosporin for you or a family member, this quick guide tells you what to expect and what to watch out for. Cephalosporins are a family of antibiotics used for many infections — from ear and throat infections to urinary and some skin infections. They work by weakening bacterial cell walls so bacteria can’t survive.
Common drugs in this group include cefalexin, cefuroxime, cefixime, and ceftriaxone. Each has different strengths, dosing schedules, and ways it’s given (some are pills, others are injections). Your prescription will name the exact one and how long to take it. Don’t skip doses and finish the full course unless your doctor says otherwise — stopping early can let the infection come back stronger.
Most people tolerate cephalosporins well. The usual side effects are stomach upset, diarrhea, and mild skin rash. A more serious concern is an allergic reaction. If you’ve had a severe penicillin allergy, tell your doctor — there’s some cross-reaction risk, though it’s lower than once thought. If you get wheezing, swelling of the face or throat, or fainting, seek emergency help.
Some cephalosporins can raise the chance of Clostridioides difficile (C. diff) diarrhea, which causes severe, watery stools. If you get heavy diarrhea, fever, or belly pain after taking antibiotics, contact your clinician. Also, a couple of older cephalosporins can cause a disulfiram-like reaction with alcohol — that means drinking can make you feel very sick. If you have kidney problems, your doctor may lower the dose because these drugs exit the body through the kidneys.
- Tell your prescriber about allergies, kidney disease, pregnancy, or breastfeeding. - Mention other meds you take — some interactions matter. - Ask whether the drug needs food or should be taken on an empty stomach. - Know how long to take it and what to expect if side effects happen.
Keep pills in their original container, check expiration dates, and store them at room temperature unless the label says otherwise. If you have leftover antibiotics, don’t save them for later — talk with your pharmacist about safe disposal.
Wondering about cefixime specifically? It’s an oral third-generation cephalosporin often used for certain urinary and respiratory infections. Dose and duration depend on the illness and your age or kidney function. If a site or seller offers cefixime, make sure you have a legitimate prescription and confirm the pharmacy’s credentials.
Buying antibiotics online can be okay if you use a licensed pharmacy. Check for a real address and phone number, look for licensing seals, read recent reviews, and never buy from sellers that skip prescriptions. Prices that look too good to be true often are. When in doubt, call the pharmacy and ask to speak with a pharmacist before ordering.
Want to be safe? Use a local pharmacy you trust or a well-known online pharmacy that requires prescriptions and offers pharmacist support. That reduces risk and helps you get correct dosing advice for you or your family.