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Tag: CNS depressants

Antihistamine Interactions with Other Sedating Medications: What You Need to Know
  • January 20, 2026
  • Comments 13
  • Medications and Supplements

Antihistamine Interactions with Other Sedating Medications: What You Need to Know

Combining first-generation antihistamines like Benadryl with other sedating drugs can cause dangerous drowsiness, breathing problems, and even delirium. Learn which medications to avoid and safer alternatives for allergies and sleep.
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