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Stendra Contraindications: Key Risks You Should Check

If you’re thinking about trying Stendra for erectile dysfunction, pause for a minute and scan this list. Knowing the red flags can keep you from nasty side effects or dangerous reactions. Below we break down who should skip Stendra, the drugs that collide with it, and simple steps to stay safe.

Who Should Avoid Stendra?

First off, anyone with a history of heart problems should be extra careful. Stendra can widen blood vessels, which may stress a weak heart. If you’ve had a heart attack, stroke, or uncontrolled angina, doctors usually say no to avanafil.

Low blood pressure is another deal‑breaker. Stendra can drop blood pressure further, leading to dizziness or fainting. If your systolic reading is under 90 mm Hg, it’s best to look for a different solution.

People taking nitrates for chest pain must stay away from Stendra. The combo can cause a sudden, severe drop in blood pressure that’s life‑threatening. Even occasional nitroglycerin patches count.

Lastly, if you’re allergic to avanafil or any of its ingredients, you should not use Stendra. Signs of an allergic reaction include rash, itching, swelling, or trouble breathing. Stop immediately and get medical help.

Common Interactions & Tips

Stendra loves to mingle with certain meds, and that can be risky. Alpha‑blockers for prostate issues (like tamsulosin) can also lower blood pressure, so take them at least 4 hours apart from Stendra.

Some antifungal drugs (ketoconazole, itraconazole) and certain antibiotics (clarithromycin, erythromycin) slow down the body’s ability to clear avanafil. That means higher levels in your system and more side effects. Talk to your pharmacist before mixing.Grapefruit juice is a sneaky culprit. It blocks the enzymes that break down Stendra, making the drug stay longer and stronger. A small glass is fine, but avoid large servings on the day you take the pill.

When you start Stendra, begin with the lowest dose—usually 50 mg. If you tolerate it well, a doctor may bump it up to 100 mg or 200 mg. Jumping straight to the max dose raises the chance of headaches, flushing, or vision changes.

Keep a short diary for the first week: note any headache, dizziness, or unusual heartbeats. If something feels off, call your healthcare provider right away. It’s better to catch an issue early than to push through it.

Remember, Stendra isn’t a cure for underlying health problems. Managing diabetes, high blood pressure, or cholesterol improves erectile function more reliably than any pill alone. Use Stendra as a short‑term boost, not a permanent fix.

Bottom line: check your heart health, blood pressure, medication list, and allergies before you pop a Stendra. When in doubt, ask your doctor for a quick screening. Staying informed means you get the benefits without the nasty surprises.

Avanafil (Stendra/Spedra) Contraindications: What Not to Mix and When to Avoid
  • September 5, 2025
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  • Medications and Supplements

Avanafil (Stendra/Spedra) Contraindications: What Not to Mix and When to Avoid

Clear, evidence-backed guide to when you should not take avanafil (Stendra/Spedra): drug interactions, health conditions, timing rules, and safer alternatives.
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Avanafil (Stendra/Spedra) Contraindications: What Not to Mix and When to Avoid
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